CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P00523
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P00523
SRC_CHICK
Gallus gallus
Proto-oncogene tyrosine-protein kinase Src

PDB Structure

PDB 5OAV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
Camara-Artigas, A.
to be published