CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Tau class glutathione S-transferase

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt Q9M9F1
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

Q9M9F1
GSTUN_ARATH
Arabidopsis thaliana
Glutathione S-transferase U23

PDB Structure

PDB 5O84
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage.
Tossounian, M.A., Van Molle, I., Wahni, K., Jacques, S., Gevaert, K., Van Breusegem, F., Vertommen, D., Young, D., Rosado, L.A., Messens, J.
Biochim. Biophys. Acta