CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.40.720
Functional Family Cellular tumor antigen p53

Enzyme Information

UniProtKB Entries (1)

P04637
P53_HUMAN
Homo sapiens
Cellular tumor antigen p53

PDB Structure

PDB 5O1H
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines.
Baud, M.G.J., Bauer, M.R., Verduci, L., Dingler, F.A., Patel, K.J., Horil Roy, D., Joerger, A.C., Fersht, A.R.
Eur J Med Chem