CATH Domain 5nfhA02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.170	Beta Complex
	2.170.220	Methionyl-trna Synthetase; domain 2
	2.170.220.10

Domain Context

CATH Clusters

Superfamily	2.170.220.10
Functional Family	Methionine--tRNA ligase

Enzyme Information

UniProtKB Entries (1)

Q38C91_TRYB2

Trypanosoma brucei brucei TREU927

Methionyl-tRNA synthetase, putative

PDB Structure

PDB	5NFH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani. Torrie, L.S., Brand, S., Robinson, D.A., Ko, E.J., Stojanovski, L., Simeons, F.R.C., Wyllie, S., Thomas, J., Ellis, L., Osuna-Cabello, M., Epemolu, O., Nuhs, A., Riley, J., MacLean, L., Manthri, S., Read, K.D., Gilbert, I.H., Fairlamb, A.H., De Rycker, M. ACS Infect Dis