CATH Domain 5n49A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain-containing protein 1

Enzyme Information

UniProtKB Entries (1)

BRD1_HUMAN

Homo sapiens

Bromodomain-containing protein 1

PDB Structure

PDB	5N49
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains. Bouche, L., Christ, C.D., Siegel, S., Fernandez-Montalvan, A.E., Holton, S.J., Fedorov, O., Ter Laak, A., Sugawara, T., Stockigt, D., Tallant, C., Bennett, J., Monteiro, O., Diaz-Saez, L., Siejka, P., Meier, J., Putter, V., Weiske, J., Muller, S., Huber, K.V.M., Hartung, I.V., Haendler, B. J. Med. Chem.