CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.930 | BirA Bifunctional Protein; domain 2 |
|
3.30.930.10 | Bira Bifunctional Protein; Domain 2 |
Domain Context
CATH Clusters
| Superfamily | Bira Bifunctional Protein; Domain 2 |
| Functional Family | Phenylalanyl-tRNA synthetase 2, mitochondrial |
Enzyme Information
| 6.1.1.20 |
Phenylalanine--tRNA ligase.
based on mapping to UniProt O95363
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).
|
UniProtKB Entries (1)
| O95363 |
SYFM_HUMAN
Homo sapiens
Phenylalanine--tRNA ligase, mitochondrial
|
PDB Structure
| PDB | 5MGH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2.
Protein Sci.
|
