CATH Domain 5m6zA02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1260	Phosphoglycerate kinase, N-terminal domain

Domain Context

CATH Clusters

Superfamily	Phosphoglycerate kinase, N-terminal domain
Functional Family	Phosphoglycerate kinase 1

Enzyme Information

2.7.2.3

Phosphoglycerate kinase.

based on mapping to UniProt P00558

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

UniProtKB Entries (1)

PGK1_HUMAN

Homo sapiens

Phosphoglycerate kinase 1

PDB Structure

PDB	5M6Z
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme. Fiorillo, A., Petrosino, M., Ilari, A., Pasquo, A., Cipollone, A., Maggi, M., Chiaraluce, R., Consalvi, V. PLoS ONE