CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphoglycerate kinase, N-terminal domain
Functional Family Phosphoglycerate kinase 1

Enzyme Information

2.7.2.3
Phosphoglycerate kinase.
based on mapping to UniProt P00558
ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

UniProtKB Entries (1)

P00558
PGK1_HUMAN
Homo sapiens
Phosphoglycerate kinase 1

PDB Structure

PDB 5M6Z
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme.
Fiorillo, A., Petrosino, M., Ilari, A., Pasquo, A., Cipollone, A., Maggi, M., Chiaraluce, R., Consalvi, V.
PLoS ONE