CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1260 | Phosphoglycerate kinase, N-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Phosphoglycerate kinase, N-terminal domain |
| Functional Family | Phosphoglycerate kinase 1 |
Enzyme Information
| 2.7.2.3 |
Phosphoglycerate kinase.
based on mapping to UniProt P00558
ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.
|
UniProtKB Entries (1)
| P00558 |
PGK1_HUMAN
Homo sapiens
Phosphoglycerate kinase 1
|
PDB Structure
| PDB | 5M1R |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme.
PLoS ONE
|