CATH Domain 5ltfA02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.2640	Arenavirus RNA polymerase

Domain Context

CATH Clusters

Superfamily	Arenavirus RNA polymerase
Functional Family	RNA-directed RNA polymerase L

Enzyme Information

2.7.7.48	RNA-directed RNA polymerase. based on mapping to UniProt P14240 Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). -!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.
3.1.-.-	Acting on ester bonds. based on mapping to UniProt P14240

UniProtKB Entries (1)

L_LYCVA

Lymphocytic choriomeningitis virus (strain Armstrong)

RNA-directed RNA polymerase L

PDB Structure

PDB	5LTF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands. Saez-Ayala, M., Yekwa, E.L., Carcelli, M., Canard, B., Alvarez, K., Ferron, F. IUCrJ