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1 keywords

CATH Domain 5lhtA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.190 D-Maltodextrin-Binding Protein; domain 2
Homologous Superfamily 3.40.190.10 Periplasmic binding protein-like II

Domain Context

CATH Clusters

Superfamily Periplasmic binding protein-like II
Functional Family ATP phosphoribosyltransferase

Enzyme Information

2.4.2.17
ATP phosphoribosyltransferase.
based on mapping to UniProt P9WMN1
1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D- ribose 1-diphosphate.
-!- Involved in histidine biosynthesis.

UniProtKB Entries (1)

P9WMN1
HIS1_MYCTU
Mycobacterium tuberculosis H37Rv
ATP phosphoribosyltransferase

PDB Structure

PDB 5LHT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Uncoupling conformational states from activity in an allosteric enzyme.
Pisco, J.P., Chiara, C., Pacholarz, K.J., Garza-Garcia, A., Ogrodowicz, R.W., Walker, P.A., Barran, P.E., Smerdon, S.J., Carvalho, L.P.S.
Nat Commun
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