CATH Classification

Domain Context

CATH Clusters

Superfamily Frizzled cysteine-rich domain
Functional Family Smoothened, frizzled class receptor

Enzyme Information

UniProtKB Entries (1)

Q98SW5
Q98SW5_XENLA
Xenopus laevis
Smoothened

PDB Structure

PDB 5KZZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
Huang, P., Nedelcu, D., Watanabe, M., Jao, C., Kim, Y., Liu, J., Salic, A.
Cell