CATH Domain 5kq5C00

Superfamily
Functional Family	-

PDB	5KQ5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy. Cameron, K.O., Kung, D.W., Kalgutkar, A.S., Kurumbail, R.G., Miller, R., Salatto, C.T., Ward, J., Withka, J.M., Bhattacharya, S.K., Boehm, M., Borzilleri, K.A., Brown, J.A., Calabrese, M., Caspers, N.L., Cokorinos, E., Conn, E.L., Dowling, M.S., Edmonds, D.J., Eng, H., Fernando, D.P., Frisbie, R., Hepworth, D., Landro, J., Mao, Y., Rajamohan, F., Reyes, A.R., Rose, C.R., Ryder, T., Shavnya, A., Smith, A.C., Tu, M., Wolford, A.C., Xiao, J. J.Med.Chem.