CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.5 | Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
|
1.20.5.1160 | Vasodilator-stimulated phosphoprotein |
Domain Context
CATH Clusters
| Superfamily | Vasodilator-stimulated phosphoprotein |
| Functional Family |
Enzyme Information
UniProtKB Entries (2)
| P09493 |
TPM1_HUMAN
Homo sapiens
Tropomyosin alpha-1 chain
|
| P03069 |
GCN4_YEAST
Saccharomyces cerevisiae S288C
General control protein GCN4
|
PDB Structure
| PDB | 5KHT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural destabilization of tropomyosin induced by the cardiomyopathy-linked mutation R21H.
Protein Sci.
|
