Note: The assignment for domain 5k75A01 was not available when the latest CATH+ database (v4_3_0) was released. The information below comes from putative assignments made in our daily snapshot: CATH-B. These assignments have gone through fewer checks than information from a CATH+ release.

CATH Classification

Domain Context

CATH Clusters

Superfamily
Functional Family -

PDB Structure

PDB 5K75
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88L265P Diffuse Large B-Cell Lymphoma.
Scott, J.S., Degorce, S.L., Anjum, R., Culshaw, J., Davies, R.D.M., Davies, N.L., Dillman, K.S., Dowling, J.E., Drew, L., Ferguson, A.D., Groombridge, S.D., Halsall, C.T., Hudson, J.A., Lamont, S., Lindsay, N.A., Marden, S.K., Mayo, M.F., Pease, J.E., Perkins, D.R., Pink, J.H., Robb, G.R., Rosen, A., Shen, M., McWhirter, C., Wu, D.
J. Med. Chem.