CATH Domain 5k48B00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.15	Metallo-beta-lactamase; Chain A
	3.60.15.10	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

Domain Context

CATH Clusters

Superfamily	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Functional Family	Class B metallo-beta-lactamase

Enzyme Information

UniProtKB Entries (1)

Q9K2N0_PSEAI

Pseudomonas aeruginosa

Beta-lactamase class B VIM-2

PDB Structure

PDB	5K48
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-beta-lactamase Inhibitors. Cain, R., Brem, J., Zollman, D., McDonough, M.A., Johnson, R.M., Spencer, J., Makena, A., Abboud, M.I., Cahill, S., Lee, S.Y., McHugh, P.J., Schofield, C.J., Fishwick, C.W.G. J. Med. Chem.