CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleic acid-binding proteins
Functional Family Exosome complex exonuclease DIS3

Enzyme Information

3.1.26.-
Endoribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt Q08162
3.1.13.-
Exoribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt Q08162

UniProtKB Entries (1)

P53859
CSL4_YEAST
Saccharomyces cerevisiae S288C
Exosome complex component CSL4

PDB Structure

PDB 5K36
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Nuclear RNA Exosome at 3.1 angstrom Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3.
Zinder, J.C., Wasmuth, E.V., Lima, C.D.
Mol.Cell