CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family protein tyrosine phosphatase type IVA 1

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt O70274
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q32NY4
CNNM3_MOUSE
Mus musculus
Metal transporter CNNM3

PDB Structure

PDB 5K24
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3.
Zhang, H., Kozlov, G., Li, X., Wu, H., Gulerez, I., Gehring, K.
Sci Rep