CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.200 | Phosphorylase Kinase; domain 1 |
|
3.30.200.20 | Phosphorylase Kinase; domain 1 |
Domain Context
CATH Clusters
| Superfamily | Phosphorylase Kinase; domain 1 |
| Functional Family | Choline kinase alpha |
Enzyme Information
| 2.7.1.82 |
Ethanolamine kinase.
based on mapping to UniProt P35790
ATP + ethanolamine = ADP + O-phosphoethanolamine.
|
| 2.7.1.32 |
Choline kinase.
based on mapping to UniProt P35790
ATP + choline = ADP + phosphocholine.
-!- Ethanolamine and its methyl and ethyl derivatives can also act as acceptors.
|
UniProtKB Entries (1)
| P35790 |
CHKA_HUMAN
Homo sapiens
Choline kinase alpha
|
PDB Structure
| PDB | 5FTG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Design, Synthesis, Crystallization and Biological Evaluation of New Symmetrical Biscationic Compounds as Selective Inhibitors of Human Choline Kinase Alpha1 (Chokalpha1)
Sci.Rep.
|