CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Acetylcholinesterase

Enzyme Information

3.1.1.7
Acetylcholinesterase.
based on mapping to UniProt P21836
Acetylcholine + H(2)O = choline + acetate.
-!- Acts on a variety of acetic esters. -!- Also catalyzes transacetylations.

UniProtKB Entries (1)

P21836
ACES_MOUSE
Mus musculus
Acetylcholinesterase

PDB Structure

PDB 5FKJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Slow-Binding Inhibition of Acetylcholinesterase by a 6-Methyluracil Alkyl-Ammonium Derivative: Mechanism and Advantages for Myasthenia Gravis Treatment.
Kharlamova, A.D., Lushchekina, S.V., Petrov, K.A., Kots, E.D., Nachon, F.V., Villard-Wandhammer, M., Zueva, I.V., Krejci, E., Reznik, V.S., Zobov, V.V., Nikolsky, E.E., Masson, P.
Biochem.J.