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1 keywords

CATH Domain 5f2lB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Tagatose 1,6-diphosphate aldolase 2

Enzyme Information

4.1.2.40
Tagatose-bisphosphate aldolase.
based on mapping to UniProt P63705
D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.
-!- Enzyme activity is stimulated by certain divalent cations. -!- Involved in the tagatose 6-phosphate pathway of lactose catabolism in bacteria.

UniProtKB Entries (1)

P63705
LACD2_STRP1
Streptococcus pyogenes serotype M1
Tagatose 1,6-diphosphate aldolase 2

PDB Structure

PDB 5F2L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
NON-STEREOSPECIFIC SUBSTRATE CLEAVAGE BY TAGATOSE-BISPHOSPHATE CLASS I ALDOLASE
LowKam, C., Liotard, B., Sygusch, J.
To Be Published
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