CATH Domain 5eroC00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.600	Farnesyl Diphosphate Synthase
	1.10.600.10	Farnesyl Diphosphate Synthase

Domain Context

CATH Clusters

Superfamily	Farnesyl Diphosphate Synthase
Functional Family

Enzyme Information

4.2.3.43	Fusicocca-2,10(14)-diene synthase. based on mapping to UniProt A2PZA5 Geranylgeranyl diphosphate = fusicocca-2,10(14)-diene + diphosphate. -!- A multifunctional enzyme with EC 2.5.1.29 activity.
2.5.1.29	Geranylgeranyl diphosphate synthase. based on mapping to UniProt A2PZA5 (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate. -!- Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors.

UniProtKB Entries (1)

FC1_PHOAM

Diaporthe amygdali

Fusicoccadiene synthase

PDB Structure

PDB	5ERO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase. Chen, M., Chou, W.K., Toyomasu, T., Cane, D.E., Christianson, D.W. Acs Chem.Biol.