CATH Domain 5e26A01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.510

Domain Context

CATH Clusters

Superfamily	3.30.420.510
Functional Family	pantothenate kinase 2, mitochondrial

Enzyme Information

2.7.1.33

Pantothenate kinase.

based on mapping to UniProt Q9BZ23

ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.

UniProtKB Entries (1)

PANK2_HUMAN

Homo sapiens

Pantothenate kinase 2, mitochondrial

PDB Structure

PDB	5E26
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate LOPPNAU, P., DONG, A., RAVICHANDRAN, M., CHENG, C., TEMPEL, W., SEITOVA, A., HUTCHINSON, A., HONG, B.S., Bountra, C., Arrowsmith, C.H., Edwards, A.M., BROWN, P.J., Structural Genomics Consortium (SGC) to be published