CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.10.20
Functional Family Transmembrane serine/threonine-protein kinase B

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P9WI81
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P9WI81
PKNB_MYCTU
Mycobacterium tuberculosis H37Rv
Serine/threonine-protein kinase PknB

PDB Structure

PDB 5E10
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site.
Prigozhin, D.M., Papavinasasundaram, K.G., Baer, C.E., Murphy, K.C., Moskaleva, A., Chen, T.Y., Alber, T., Sassetti, C.M.
J.Biol.Chem.