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1 keywords

CATH Domain 5conA00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.70 Cathepsin D, subunit A; domain 1
Homologous Superfamily 2.40.70.10 Acid Proteases

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

G0X8E8
G0X8E8_9HIV1
Human immunodeficiency virus 1
Pol protein

PDB Structure

PDB 5CON
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir.
Aoki, M., Hayashi, H., Yedidi, R.S., Martyr, C.D., Takamatsu, Y., Aoki-Ogata, H., Nakamura, T., Nakata, H., Das, D., Yamagata, Y., Ghosh, A.K., Mitsuya, H.
J.Virol.
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