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1 keywords

CATH Domain 5cksB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Phospho-2-dehydro-3-deoxyheptonate aldolase

Enzyme Information

2.5.1.54
3-deoxy-7-phosphoheptulonate synthase.
based on mapping to UniProt P0AB91
Phosphoenolpyruvate + D-erythrose 4-phosphate + H(2)O = 3-deoxy-D- arabino-hept-2-ulosonate 7-phosphate + phosphate.
-!- Formerly EC 4.1.2.15.

UniProtKB Entries (1)

P0AB91
AROG_ECOLI
Escherichia coli K-12
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive

PDB Structure

PDB 5CKS
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Potent Inhibition of 3-Deoxy-d-arabinoheptulosonate-7-phosphate (DAHP) Synthase by DAHP Oxime, a Phosphate Group Mimic.
Balachandran, N., Heimhalt, M., Liuni, P., To, F., Wilson, D.J., Junop, M.S., Berti, P.J.
Biochemistry
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