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1 keywords

CATH Domain 5bo2B02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.1030 Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2
Homologous Superfamily 3.40.1030.10 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
Functional Family Anthranilate phosphoribosyltransferase

Enzyme Information

2.4.2.18
Anthranilate phosphoribosyltransferase.
based on mapping to UniProt A5U4M0
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).

UniProtKB Entries (1)

A5U4M0
TRPD_MYCTA
Mycobacterium tuberculosis H37Ra
Anthranilate phosphoribosyltransferase

PDB Structure

PDB 5BO2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Binding and mimicking of the phosphate-rich substrate, PRPP.
Evans, G.L., Baker, E.N., Lott, J.S.
To be Published
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