CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.620 | HUPs |
Domain Context
CATH Clusters
| Superfamily | HUPs |
| Functional Family |
Enzyme Information
| 2.8.1.15 |
tRNA-5-methyluridine(54) 2-sulfurtransferase.
based on mapping to UniProt Q72LF3
ATP + [TtuB sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + 5-methyluracil(54) in tRNA + H(2)O = AMP + diphosphate + 5-methyl-2- thiouracil(54) in tRNA + [TtuB sulfur-carrier protein]-Gly-Gly.
-!- The enzyme, found in thermophilic bacteria such as Thermus thermophilus and archaea such as Pyrococcus horikoshii, modifies the ribothymidine (5-methyluridine) residue at position 54 of tRNAs.
|
UniProtKB Entries (1)
| Q72LF3 |
TTUA_THET2
Thermus thermophilus HB27
TRNA-5-methyluridine(54) 2-sulfurtransferase
|
PDB Structure
| PDB | 5B4F |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Biochemical and structural characterization of oxygen-sensitive 2-thiouridine synthesis catalyzed by an iron-sulfur protein TtuA
Proc. Natl. Acad. Sci. U.S.A.
|
