×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 5aviC00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Oxysterols receptor LXR-alpha isoform 1

Enzyme Information

UniProtKB Entries (1)

Q15788
NCOA1_HUMAN
Homo sapiens
Nuclear receptor coactivator 1

PDB Structure

PDB 5AVI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery and structure-guided optimization of tert-butyl 6-(phenoxymethyl)-3-(trifluoromethyl)benzoates as liver X receptor agonists
Matsui, Y., Yamaguchi, T., Yamazaki, T., Yoshida, M., Arai, M., Terasaka, N., Honzumi, S., Wakabayashi, K., Hayashi, S., Nakai, D., Hanzawa, H., Tamaki, K.
Bioorg.Med.Chem.Lett.
CATH-Gene3D is a Global Biodata Core Resource Learn more...