1 keywords

CATH Domain 4yyyA01

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.970 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3
Homologous Superfamily 1.20.970.10 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C

Domain Context

CATH Clusters

Superfamily Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C
Functional Family Thymidine phosphorylase

Enzyme Information

2.4.2.4
Thymidine phosphorylase.
based on mapping to UniProt Q7CP66
Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.
-!- In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6. -!- Formerly EC 2.4.2.23.

UniProtKB Entries (1)

Q7CP66
TYPH_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Thymidine phosphorylase

PDB Structure

PDB 4YYY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural investigation of the thymidine phosphorylase from Salmonella typhimurium in the unliganded state and its complexes with thymidine and uridine.
Balaev, V.V., Lashkov, A.A., Gabdulkhakov, A.G., Dontsova, M.V., Seregina, T.A., Mironov, A.S., Betzel, C., Mikhailov, A.M.
Acta Crystallogr.,Sect.F