CATH Domain 4y5oA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1160	Paired amphipathic helix 2 (pah2 repeat)
	1.20.1160.20

Domain Context

CATH Clusters

Superfamily	1.20.1160.20
Functional Family	Cerebral cavernous malformation 2

Enzyme Information

UniProtKB Entries (1)

M3K3_HUMAN

Homo sapiens

Mitogen-activated protein kinase kinase kinase 3

PDB Structure

PDB	4Y5O
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex. Fisher, O.S., Deng, H., Liu, D., Zhang, Y., Wei, R., Deng, Y., Zhang, F., Louvi, A., Turk, B.E., Boggon, T.J., Su, B. Nat Commun