CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphofructokinase domain
Functional Family ATP-dependent 6-phosphofructokinase

Enzyme Information

2.7.1.11
6-phosphofructokinase.
based on mapping to UniProt Q01813
ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.
-!- D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors. -!- UTP, CTP and ITP can act as donors. -!- Not identical with EC 2.7.1.105.

UniProtKB Entries (1)

Q01813
PFKAP_HUMAN
Homo sapiens
ATP-dependent 6-phosphofructokinase, platelet type

PDB Structure

PDB 4XYK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations.
Webb, B.A., Forouhar, F., Szu, F.E., Seetharaman, J., Tong, L., Barber, D.L.
Nature