CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.920 | SPRY domain |
Domain Context
CATH Clusters
| Superfamily | 2.60.120.920 |
| Functional Family | ATP-dependent RNA helicase DDX1 |
Enzyme Information
| 3.6.4.13 |
RNA helicase.
based on mapping to UniProt Q92499
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).
|
UniProtKB Entries (1)
| Q92499 |
DDX1_HUMAN
Homo sapiens
ATP-dependent RNA helicase DDX1
|
PDB Structure
| PDB | 4XW3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of the SPRY domain of the human RNA helicase DDX1, a putative interaction platform within a DEAD-box protein.
Acta Crystallogr.,Sect.F
|
