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1 keywords

CATH Domain 4wv1B02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin heavy constant gamma 1

Enzyme Information

UniProtKB Entries (1)

P21802
FGFR2_HUMAN
Homo sapiens
Fibroblast growth factor receptor 2

PDB Structure

PDB 4WV1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Redesigning a Monospecific Anti-FGFR3 Antibody to Add Selectivity for FGFR2 and Expand Antitumor Activity.
Yin, Y., Djakovic, S., Marsters, S., Tien, J., Peng, J., Tremayne, J., Lee, G., Neve, R.M., Wu, Y., Merchant, M., Ashkenazi, A., Carter, P.J.
Mol.Cancer Ther.
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