CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family serine/threonine-protein kinase unc-51 isoform X1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O75385
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O75385
ULK1_HUMAN
Homo sapiens
Serine/threonine-protein kinase ULK1

PDB Structure

PDB 4WNO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors.
Lazarus, M.B., Novotny, C.J., Shokat, K.M.
Acs Chem.Biol.