CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.2300 | Neutral/alkaline non-lysosomal ceramidase, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Neutral/alkaline non-lysosomal ceramidase, C-terminal domain |
| Functional Family | N-acylsphingosine amidohydrolase 2 |
Enzyme Information
| 3.5.1.- |
In linear amides.
based on mapping to UniProt Q9NR71
|
| 3.5.1.23 |
Ceramidase.
based on mapping to UniProt Q9NR71
N-acylsphingosine + H(2)O = a carboxylate + sphingosine.
|
UniProtKB Entries (1)
| Q9NR71 |
ASAH2_HUMAN
Homo sapiens
Neutral ceramidase
|
PDB Structure
| PDB | 4WGK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase.
Structure
|