CATH Domain 4uyeB00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain-containing protein 1

Enzyme Information

UniProtKB Entries (1)

BRPF1_HUMAN

Homo sapiens

Peregrin

PDB Structure

PDB	4UYE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	1,3-Dimethyl Benzimidazolones are Potent, Selective Inhibitors of the Brpf1 Bromodomain. Demont, E.H., Bamborough, P., Chung, C.W., Craggs, P.D., Fallon, D., Gordon, L.J., Grandi, P., Hobbs, C.I., Hussain, J., Jones, E.J., Le Gall, A., Michon, A.M., Mitchell, D.J., Prinjha, R.K., Roberts, A.D., Sheppard, R.J., Watson, R.J. Acs Med.Chem.Lett.