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1 keywords

CATH Domain 4tvhA00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.70 Cathepsin D, subunit A; domain 1
Homologous Superfamily 2.40.70.10 Acid Proteases

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

Q90EA1
Q90EA1_9HIV1
Human immunodeficiency virus 1
Protease

PDB Structure

PDB 4TVH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Distinguishing Binders from False Positives by Free Energy Calculations: Fragment Screening Against the Flap Site of HIV Protease.
Deng, N., Forli, S., He, P., Perryman, A., Wickstrom, L., Vijayan, R.S., Tiefenbrunn, T., Stout, D., Gallicchio, E., Olson, A.J., Levy, R.M.
J.Phys.Chem.B
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