CATH Domain 4tu9A02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.330	RRM (RNA recognition motif) domain

Domain Context

CATH Clusters

Superfamily	3.30.70.330
Functional Family	U2 snRNP auxiliary factor large subunit

Enzyme Information

UniProtKB Entries (1)

U2AF2_HUMAN

Homo sapiens

Splicing factor U2AF 65 kDa subunit

PDB Structure

PDB	4TU9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA. Agrawal, A.A., McLaughlin, K.J., Jenkins, J.L., Kielkopf, C.L. Proc.Natl.Acad.Sci.USA