CATH Classification

Domain Context

CATH Clusters

Superfamily Periplasmic binding protein-like II
Functional Family

Enzyme Information

2.5.1.2
Thiamine pyridinylase.
based on mapping to UniProt P45741
Thiamine + pyridine = 1-((4-amino-2-methylpyrimidin-5- yl)methyl)pyridinium + 4-methyl-5-(2-hydroxyethyl)thiazole.
-!- Various bases and thiol compounds can act instead of pyridine.

UniProtKB Entries (1)

P45741
THI1_PANTH
Paenibacillus thiaminolyticus
Thiaminase-1

PDB Structure

PDB 4THI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of thiaminase-I from Bacillus thiaminolyticus at 2.0 A resolution.
Campobasso, N., Costello, C.A., Kinsland, C., Begley, T.P., Ealick, S.E.
Biochemistry