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1 keywords

CATH Domain 4qg0C01

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.3210 Hypothetical protein af1432
Homologous Superfamily 1.10.3210.10 Hypothetical protein af1432

Domain Context

CATH Clusters

Superfamily Hypothetical protein af1432
Functional Family Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Enzyme Information

3.1.5.-
Triphosphoric monoester hydrolases.
based on mapping to UniProt Q9Y3Z3

UniProtKB Entries (1)

Q9Y3Z3
SAMH1_HUMAN
Homo sapiens
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

PDB Structure

PDB 4QG0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates.
Koharudin, L.M., Wu, Y., DeLucia, M., Mehrens, J., Gronenborn, A.M., Ahn, J.
J.Biol.Chem.
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