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CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family

Enzyme Information

2.1.1.44
L-histidine N(alpha)-methyltransferase.
based on mapping to UniProt A0R5M8
3 S-adenosyl-L-methionine + L-histidine = 3 S-adenosyl-L-homocysteine + hercynine.
-!- Part of the biosynthetic pathway of ergothioneine.

UniProtKB Entries (1)

A0R5M8
EGTD_MYCS2
Mycolicibacterium smegmatis MC2 155
Histidine N-alpha-methyltransferase

PDB Structure

PDB 4PIM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Ergothioneine Biosynthetic Methyltransferase EgtD Reveals the Structural Basis of Aromatic Amino Acid Betaine Biosynthesis.
Vit, A., Misson, L., Blankenfeldt, W., Seebeck, F.P.
Chembiochem
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