CATH Classification

Domain Context

CATH Clusters

Superfamily Anticodon-binding domain
Functional Family histidine--tRNA ligase, cytoplasmic isoform X1

Enzyme Information

6.1.1.21
Histidine--tRNA ligase.
based on mapping to UniProt P12081
ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).

UniProtKB Entries (1)

P12081
SYHC_HUMAN
Homo sapiens
Histidine--tRNA ligase, cytoplasmic

PDB Structure

PDB 4PHC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Comparison of histidine recognition in human and trypanosomatid histidyl-tRNA synthetases.
Koh, C.Y., Wetzel, A.B., de van der Schueren, W.J., Hol, W.G.
Biochimie