CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.70 | Alpha-Beta Plaits | |
3.30.70.1230 | Nucleotide cyclase |
Domain Context
CATH Clusters
Superfamily | Nucleotide cyclase |
Functional Family | Adenylate cyclase type 10 |
Enzyme Information
4.6.1.1 |
Adenylate cyclase.
based on mapping to UniProt Q96PN6
ATP = 3',5'-cyclic AMP + diphosphate.
-!- Also acts on dATP to form 3',5'-cyclic dAMP. -!- Requires pyruvate. -!- Activated by NAD(+) in presence of EC 2.4.2.31.
|
UniProtKB Entries (1)
Q96PN6 |
ADCYA_HUMAN
Homo sapiens
Adenylate cyclase type 10
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PDB Structure
PDB | 4OYA |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem
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