CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.1100
Functional Family Cysteine synthase

Enzyme Information

2.5.1.47
Cysteine synthase.
based on mapping to UniProt P45040
O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
-!- Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors. -!- Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53. -!- Formerly EC 4.2.99.8.

UniProtKB Entries (2)

P45040
CYSK_HAEIN
Haemophilus influenzae Rd KW20
Cysteine synthase
P29847
CYSE_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Serine acetyltransferase

PDB Structure

PDB 4NU8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of O-acetylserine sulfhydrylase from Haemophilus influenzae in complex with high affinity inhibitory peptide from serine acetyl transferase of Salmonella Typhimurium at 2.0 A
Ekka, M.K., Kaushik, A., Singh, A.K., Kumaran, S.
To be Published