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CATH Classification

Domain Context

CATH Clusters

Superfamily Membrane associated eicosanoid/glutathione metabolism-like domain
Functional Family Leukotriene C4 synthase

Enzyme Information

4.4.1.20
Leukotriene-C(4) synthase.
based on mapping to UniProt Q60860
Leukotriene C(4) = leukotriene A(4) + glutathione.
-!- The reaction proceeds in the direction of addition. -!- Not identical with EC 2.5.1.18. -!- Formerly EC 2.5.1.37.

UniProtKB Entries (1)

Q60860
LTC4S_MOUSE
Mus musculus
Leukotriene C4 synthase

PDB Structure

PDB 4NTA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mus Musculus LTC4 synthase in apo form
Niegowski, D., Rinaldo-Matthis, A., Kleinschmidt, T., Qureshi, A.A., Haeggstrom, J.Z.
To be Published
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