CATH Domain 4npyH01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Immunoglobulin heavy variable 4-30-4

Enzyme Information

UniProtKB Entries (1)

Q6GMX6_HUMAN

Homo sapiens

IGH@ protein

PDB Structure

PDB	4NPY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies. Sok, D., Laserson, U., Laserson, J., Liu, Y., Vigneault, F., Julien, J.P., Briney, B., Ramos, A., Saye, K.F., Le, K., Mahan, A., Wang, S., Kardar, M., Yaari, G., Walker, L.M., Simen, B.B., St John, E.P., Chan-Hui, P.Y., Swiderek, K., Kleinstein, S.H., Alter, G., Seaman, M.S., Chakraborty, A.K., Koller, D., Wilson, I.A., Church, G.M., Burton, D.R., Poignard, P. Plos Pathog.