CATH Domain 4nefA00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1080	Glycerol uptake facilitator protein
	1.20.1080.10	Glycerol uptake facilitator protein.

Domain Context

CATH Clusters

Superfamily	Glycerol uptake facilitator protein.
Functional Family	Lens fiber major intrinsic

Enzyme Information

UniProtKB Entries (1)

AQP2_HUMAN

Homo sapiens

Aquaporin-2

PDB Structure

PDB	4NEF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	X-ray structure of human aquaporin 2 and its implications for nephrogenic diabetes insipidus and trafficking Frick, A., Eriksson, U.K., de Mattia, F., Oberg, F., Hedfalk, K., Neutze, R., de Grip, W.J., Deen, P.M., Tornroth-Horsefield, S. Proc.Natl.Acad.Sci.USA