CATH Domain 4ncjB01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family

Enzyme Information

UniProtKB Entries (1)

RAD50_PYRFU

Pyrococcus furiosus DSM 3638

DNA double-strand break repair Rad50 ATPase

PDB Structure

PDB	4NCJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. Deshpande, R.A., Williams, G.J., Limbo, O., Williams, R.S., Kuhnlein, J., Lee, J.H., Classen, S., Guenther, G., Russell, P., Tainer, J.A., Paull, T.T. Embo J.