CATH Domain 4m3dA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.357	Tetracycline Repressor; domain 2
	1.10.357.10	Tetracycline Repressor, domain 2

Domain Context

CATH Clusters

Superfamily	Tetracycline Repressor, domain 2
Functional Family	HTH-type transcriptional regulator EthR

Enzyme Information

UniProtKB Entries (1)

ETHR_MYCTU

Mycobacterium tuberculosis H37Rv

HTH-type transcriptional regulator EthR

PDB Structure

PDB	4M3D
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking Approaches. Villemagne, B., Flipo, M., Blondiaux, N., Crauste, C., Malaquin, S., Leroux, F., Piveteau, C., Villeret, V., Brodin, P., Villoutreix, B.O., Sperandio, O., Soror, S.H., Wohlkonig, A., Wintjens, R., Deprez, B., Baulard, A.R., Willand, N. J.Med.Chem.